Serratio Ds

Generic Name: Serratiopeptidase

Anti-inflammatory & anti-tumefacient oral enzyme preparation

Description
Serratio DS.

Actions
Elimination of inflammatory edema and swelling:
Improves the circulation at the inflammatory focus by breaking down abnormal exudates and protein and by promoting the absorption of the decomposed products through the blood and lymphatic vessels.

Acceleration of liquefaction and elimination of sputum, pus and hematoma:
Accelerates the elimination of sputum, pus and hematoma by breaking down and liquefying mucous secretions and fibrin clots.

Enhancement of the action of antibiotics:
Increases the concentration of antibiotics in the focus of infection.
Indications
• Inflammation after operation and traumatic injury.
• As concomitant therapy for elimination of inflammatory edema and swelling in the following diseases
Otorhinolaryngology…………………….. Sinusitis
Gynecology………………………………….. Engorgement of the breast
Urology………………………………………… Cystitis, epididymitis
Dentistry & Oral surgery………………. Pericoronitis of the wisdom tooth, alveolar abscess

– Inadequate expectoration of sputum in the following diseases
Bronchitis, bronchial asthma, and concomitant therapy with antitubercular agents in pulmonary tuberculosis.
– Inadequate expectoration of sputum after anesthesia.
Administration and Dosage
Adults
Usually, for adults, one tablet orally, three times daily after meal without chewing. Dosage may be increased according to condition.

Use in pregnancy and lactation
There is no specific data to be described.

Contraindications
Patients with a history of hypersensitivity to the ingredients of this drug.

Precautions
In patients with blood coagulation abnormalities, severe hepatic and renal disturbances or under treatment with anti-coagulants, DANZEN should be given under careful observation. DANZEN may occasionally cause gastrointestinal disturbances such as anorexia, gastric discomfort and nausea. Administration should be discontinued when hypersensitive symptoms, such as eruption, appear.

Drug interaction
There is no specific data to be described.

Adverse Drug Reactions
Skin: Stevens-Johnson syndrome, Toxic epidermal necrolysis, Rash, Pruritus Hypersensitivity : Shock, Anaphylactic symptoms Hepatic: Hepatitis, Jaundice

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